Dr. Michael Weinblatt is a renowned rheumatology expert, accompanied by Grace Wright, a physician skilled in autoimmune diseases, Richard Conway, a treatment methodology authority, and Joel Kremer, a specialist in rheumatic conditions. They delve into the intricacies of methotrexate as a treatment option. Topics include the critical balance of folate supplementation, managing liver health, and the impacts of alcohol on treatment. They also discuss methotrexate's role alongside vaccinations and its use in patients with interstitial lung disease, emphasizing the necessity of careful monitoring and personalized treatment strategies.