The Proof with Simon Hill

How the microbiome affects metabolism and body weight | Dr Will Bulsiewicz, MD

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Aug 21, 2023
Guest
Will Bulsiewicz
Dr Will Bulsiewicz, a leading authority in gut health, discusses how the microbiome affects metabolism and body weight. Topics include dietary fiber's impact on disease prevention, comparing ketogenic and plant-based diets, increasing dietary fiber intake, and the connection between the microbiome and fat metabolism. Dr Bulsiewicz also shares strategies to boost metabolism and promote brown fat activation.
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ANECDOTE

Proud Owner Of A Friendly Parasite

  • Dr Bulsiewicz jokingly revealed he carries the parasite blastocystis and called himself 'a father of a blastocystis.'
  • He noted blastocystis prevalence is low in Americans (5%) but higher in the UK (20%).
INSIGHT

Microbiome Is A Metabolic Organ

  • The gut microbiome is an evolved, symbiotic ecosystem concentrated in the colon that influences digestion, immunity, hormones, and metabolism.
  • Microbes break down fiber into short-chain fatty acids (butyrate, acetate, propionate) which mediate many host physiological effects.
INSIGHT

Microbiome Can Drive Body Weight

  • Transferring microbiomes from lean or obese humans into germ-free mice changes the mice's weight despite identical diets.
  • Microbiome composition can drive host energy balance independent of calorie intake.
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