In a trending paper published by Oncotarget on March 2, 2021, titled, “Quantitative proteome profiling stratifies fibroepithelial lesions of the breast,” researchers from India conducted a study to better characterize phyllodes tumors and other breast fibroepithelial lesions in order to improve diagnosis and treatment for patients.
To begin identifying the differentially expressed genes and proteins among FAD and PTs in benign, borderline, and malignant states, the researchers conducted quantitative global proteomics on Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections. They conducted a principal component analysis of the protein expression matrix to identify the overlapping proteomic profiles among FELs.
“Interestingly, we observed FADs and benign PTs clustered together compared to borderline and malignant ones, albeit with overlapping protein expression profiles.”
Read the full study: doi.org/10.18632/oncotarget.27889
Oncotarget Volume 12, Issue 6: oncotarget.com/archive/v12/i6/
The Trending with Impact series highlights Oncotarget publications attracting higher visibility among readers around the world online, in the news, and on social media—beyond normal readership levels.
More from Trending with Impact: https://www.oncotarget.org/tag/trending-with-impact/
About Oncotarget:
Oncotarget is a bi-weekly, peer-reviewed, open access biomedical journal covering research on all aspects of oncology.
To learn more about Oncotarget, please visit www.oncotarget.com or follow us:
SoundCloud - @oncotarget
Facebook - www.facebook.com/Oncotarget/
Twitter - twitter.com/oncotarget
LinkedIn - www.linkedin.com/company/oncotarget
Instagram - www.instagram.com/oncotargetjrnl/
YouTube - www.youtube.com/OncotargetYouTube
Pinterest - www.pinterest.com/oncotarget/
Reddit - www.reddit.com/user/Oncotarget/
Oncotarget is published by Impact Journals, LLC please visit www.ImpactJournals.com or connect with @ImpactJrnls
Media Contact
MEDIA@IMPACTJOURNALS.COM
18009220957x105
Oncotarget