
As a Woman How Insulin Resistance Impacts Your Energy, Hormones, and Fertility | Dr. Arti Thangudu
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Nov 4, 2025 Dr. Arti Thangudu, a triple board-certified physician specializing in metabolic health, joins to unravel the complexities of insulin resistance. She explains how this condition can lead to energy deficits, hormonal imbalances, and fertility issues. Listeners learn about early warning signs and lifestyle changes—like dietary shifts and exercise—that can enhance insulin sensitivity. Dr. Thangudu also discusses the significance of sleep and investigates potential supplements and medical treatments, empowering women to take control of their health.
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Insulin Is More Than Blood Sugar Control
- Insulin is a hormone that lowers blood sugar and also regulates fat usage and storage.
- Insulin resistance means cells stop responding so the body raises insulin, which worsens weight gain and metabolic function.
The Vicious Cycle Of Insulin Resistance
- Insulin resistance occurs when cells won't open the 'gate' to let glucose in, so the pancreas secretes more insulin.
- That higher insulin then promotes weight gain, creating a self-reinforcing vicious cycle.
Insulin Resistance Affects Whole-Body Organs
- Insulin resistance can affect multiple organs including muscle and liver, so problems compound across systems.
- A fatty, insulin-resistant liver keeps producing glucose even when insulin levels are high, worsening hyperglycemia.



