Defining Endpoints and Outcome Measures in Clinical Trials

When considering clinical outcome assessments (COAs) in intervention development, the focus lies on specifying endpoints relevant to the population, intervention, context, and hypothesis. Endpoints encapsulate measures, including timing and estimated treatment effects, aiming to demonstrate the impact of interventions on patients' lives. Careful consideration of when and how to measure endpoints is vital, balancing the need for comprehensive data collection with participant burden.