More Plates More Dates TRT Dosing And Frequency Breakdown With Dr. Peter Attia
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Jun 25, 2024 
Dr. Peter Attia, an expert in TRT dosing, discusses the benefits of varying dosing frequencies in TRT and the importance of achieving consistent serum levels with injections. The podcast covers the significance of daily injections for minimizing hormone suppression, the advantages of nasal testosterone formulations, and the benefits of subcutaneous injections for sustained release and higher total T levels.
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Injection Frequency
- Inject testosterone at least twice a week for optimal hormone levels.
- Once-weekly injections are the minimum, but not ideal for stable concentrations.
FSHLH Suppression and Peaks
- Higher testosterone peaks result in more FSHLH suppression.
- Small daily doses show less suppression compared to larger weekly doses.
Frequent Injections and Side Effects
- Frequent injections minimize aromatization and 5-alpha reduction spikes.
- Large, infrequent doses cause dramatic hormonal fluctuations with various side effects.