TRT Dosing And Frequency Breakdown With Dr. Peter Attia
Jun 25, 2024
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Dr. Peter Attia, an expert in TRT dosing, discusses the benefits of varying dosing frequencies in TRT and the importance of achieving consistent serum levels with injections. The podcast covers the significance of daily injections for minimizing hormone suppression, the advantages of nasal testosterone formulations, and the benefits of subcutaneous injections for sustained release and higher total T levels.
Injecting testosterone more frequently, like twice a week, maintains steady hormone levels for better results.
Daily testosterone injections may lead to lower FSHLH suppression and fewer side effects, enhancing treatment effectiveness.
Deep dives
Optimal Injection Frequency for Hormone Concentrations
Injecting testosterone more frequently, such as twice a week, is essential for maintaining steady hormone levels and achieving optimal results. Continuous injections help prevent hormonal spikes and maintain balanced concentrations, improving overall well-being and performance.
Benefits of Daily Testosterone Injections
Daily testosterone injections can result in lower FSHLH suppression compared to less frequent doses, indicating a potential advantage in hormone regulation. By administering smaller doses daily, individuals may experience reduced side effects and a more stable hormonal profile, enhancing the effectiveness of the treatment.
Subcutaneous vs. Intramuscular Injection Impact
Subcutaneous injections may provide a sustained release effect, leading to higher total testosterone levels over time. While the data supporting this claim may not be definitive, subcutaneous dosing offers a potential advantage in maintaining consistent hormone levels. The method of injection, whether subcutaneous or intramuscular, can significantly impact the drug's onset of action and overall effectiveness in hormone therapy.