AMA #9: Kratom Risks, Does Infrared Sauna Work & Journaling Benefits
Jul 28, 2023
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Learn about the controversy surrounding kratom and its association with the opioid crisis. Explore the therapeutic uses of cannabis and the risks of high concentration THC. Discover the importance of funding research for mental health, physical health, and performance.
Kratom can be effective for weaning off potent opioids but should be used with caution due to its addictive potential.
Individuals with a strong liking for opioids should completely avoid kratom to prevent escalating dosage and withdrawal symptoms.
Deep dives
The Effects of Kratom: A Controversial Substance
Kratom is a substance derived from a tree in Indonesia that has stimulant effects when consumed in low dosages. However, at higher dosages, it acts as an analgesic and sedative, similar to opioids, making it a controversial topic due to the ongoing opioid crisis. While some people have successfully used kratom to wean themselves off potent opioids like morphine and hydrocodone, it has been shown to be habit-forming and addictive, especially at higher dosages. As a result, it is recommended to avoid kratom if possible, and if already taking it, to be cautious about dosage and consider tapering off completely.
Different Response to Opioids and Kratom
Individuals differ in their response to opioids, and this is no different with kratom. Between 10% and 40% of people have a potent liking for opioids, making them more vulnerable to addiction. These individuals should avoid kratom completely, as they are likely to escalate their dosage and experience significant withdrawal symptoms if they try to quit. It's important to acknowledge that some people may have successfully used kratom to wean off stronger opioids, but the ultimate goal should be to be completely free of all opioids.
Understanding Kratom's Pharmacology and Risks
Kratom acts on the mu opioid receptor, similar to more potent opioids like morphine and hydrocodone, albeit with lower potency. It triggers pain relief, mild euphoria, and changes in perception. While at low to moderate dosages, it does not suppress respiration like other opioids, when combined with alcohol or higher dosages, it can lead to respiratory failure. Death from using kratom alone is rare, but the risk increases with higher dosages and in combination with other substances. Due to the lack of regulation surrounding kratom supplements, it is important to approach kratom with caution and consider the potential risks and addictive potential.
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