The surprising ways the microbiome affects our brain development, emotions, and sex lives
May 30, 2024
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Dr. James Kinross from Imperial College London discusses the impact of microbiomes on brain health, emotions, and even potential for love potions. Topics include microbiome diversity, fecal transplants for addiction, microbial sample administration methods, microbiomes in mate selection, hormone production, fertility, and the effects of Westernized diets and pollutants on microbiomes.
Microbiomes impact brain health and emotions, potentially influencing conditions like Alzheimer's and addiction.
Fecal transplantation can treat addiction by targeting specific microbes, showing promise in altering addictive behaviors.
Deep dives
The Impact of Microbiomes on Brain Health
Microbiomes play a crucial role in brain health, influencing brain development and immune system function. Studies suggest that an unhappy gut in early development may lead to potential brain health issues later in life, such as Alzheimer's and dementia. Differences in microbiomes have been observed in individuals with depression and anxiety, indicating a link between gut health and emotional well-being. Targeting the microbiome could be a viable therapy for mental health conditions.
Microbiomes and Addiction
Studies have shown a connection between specific microbes and addiction, with evidence suggesting that certain microbes may impact addictive behaviors. Fecal transplantation has been considered as a potential treatment for addiction, showing promise in addressing conditions like alcohol addiction. Microbiomes can affect how individuals respond to drugs, impacting addiction susceptibility and treatment outcomes.
Fecal Microbiota Transplantation for Health
Fecal microbiota transplantation (FMT) involves transferring an entire microbial community to reset the gut ecosystem. FMT has shown effectiveness in treating conditions like post-C. difficile infection and inflammatory bowel disease by restoring gut ecology and immune system balance. Donor selection is crucial, considering factors like health status, microbial diversity, and compatibility for successful FMT outcomes.
Microbiomes and Mate Selection
Microbiomes may influence mate selection through social group interactions, external appearance, scent, and hormonal regulation. Microbes play a role in skin health, pheromone signaling, and hormone metabolism, affecting how individuals perceive potential partners. While a hypothetical love potion based on microbiome manipulation is plausible, the subtle interplay of microbiomes in mate selection adds complexity to human relationships.
We humans are never truly alone. This is because our bodies are colonised by vast numbers of microscopic organisms that can be found living everywhere from the surface of our skin to deep within our guts.
Collectively, this population of microbes is known as the human microbiome, and they play a key role in maintaining our health and wellbeing.
In this episode we catch up with Dr James Kinross, a colorectal surgeon and researcher based and Imperial College London and author of the new book Dark Matter: The new science of the microbiome.
He tells us about the fascinating ways that our microbiomes can impact our brain health, regulate our emotions and if we could ever use them to make an effective love potion.