The mindbodygreen Podcast 628: The truth about lean muscle, GLP-1s & women’s metabolism | Ana Kausel, M.D.
Dec 14, 2025
Dr. Ana Kausel, a board-certified endocrinologist specializing in women's health, delves into the secrets of metabolic strength and nutrition. She shares her personal journey of muscle gain, emphasizing the necessity of carbohydrates for effective strength training. Ana discusses the personalized approach to GLP-1 dosages for weight management and the importance of balancing protein and fat. She highlights the complexities of female hormone testing and offers insights on dietary choices for optimal health, advocating for a Mediterranean-style eating philosophy.
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Personal Muscle Transformation
- Ana Kausel described gaining nine pounds of lean muscle and losing 7% body fat over ~10 months through structured training and nutrition.
- She credited a coach for giving specific macros and a strength program that unlocked steady progress.
Titrate GLP-1s Slowly With Guidance
- Adjust GLP-1 dosing slowly and work with a clinician rather than chasing a fixed
Train With Structured Splits
- Structure strength training into splits and prioritize progressive overload to build muscle.
- Rest fully between heavy sets (1.5–2 minutes) and slowly increase training frequency as strength improves.