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Siim Land Podcast
#374 Longevity Secrets of Centenarians - Dr Nir Barzilai
Sep 2, 2023
Dr Nir Barzilai, longevity researcher, discusses the secrets of long-living centenarians, genes that make you live longer, and how to turn on your longevity genes. He also explores the benefits of metformin for slowing down aging and the potential side effects.
47:52
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Quick takeaways
- Genetic and environmental factors contribute to the longevity of centenarians, providing insights for targeted interventions to delay aging and prevent age-related diseases.
- Metformin, a drug commonly used for diabetes, holds promise as an anti-aging intervention due to its impact on multiple hallmarks of aging and positive outcomes in reducing various diseases.
Deep dives
Discovering Longevity Genes in Centenarians
Research on centenarians has revealed that the genes associated with their longevity are remarkably similar to what has been observed in animals. The focus of the study is to identify genetic and environmental factors that contribute to the exceptionally long lives of centenarians. Although there are similarities between animals and humans in terms of aging pathways, it is crucial to study actual human outcomes to better understand the scientific basis of longevity. The study investigates the influence of both genetic and environmental factors on extreme human longevity.
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