The Plant Free MD with Dr Anthony Chaffee

Episode 149: Is Being In Ketosis Harmful Long-term? Here's The Evidence

Aug 10, 2023

Richard Smith, a keto-pro, joins Dr. Anthony Chaffee on a deep dive into the claims that long-term ketosis is harmful. They discuss cortisol's role in weight loss struggles, the effects of a carbohydrate-restricted diet on body composition and hormones, the influence of industry-funded research, and the health effects of sugar. They also explore the hype around high fructose corn syrup, the impact of paid content on social media, and the glucose-cortisol link in adaptation to a ketogenic diet. Finally, they touch on the effect of a ketogenic carnival lifestyle on insulin sensitivity and diet for anxiety and cholesterol.

02:09:47

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Episode guests

Richard Smith

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Episode notes

Podcast summary created with Snipd AI

Quick takeaways

High fructose corn syrup and cane sugar have similar chemical compositions and metabolize in the same way in the body, leading to similar health effects.

Honey, despite containing other nutrients, can still lead to negative health effects due to its fructose content like other sugars.

Claims that there is a significant difference in health effects between high fructose corn syrup and cane sugar should be viewed skeptically and critically analyzed.

The metabolic inflexibility of cancer cells relies on glucose as their primary fuel source, debunking the claim that fat feeds cancer cells.

Ketogenic diets have shown efficacy in treating cancer by limiting carbohydrate intake and disrupting the metabolic pathways of cancer cells.

Deep dives

The Similarities Between High Fructose Corn Syrup and Cane Sugar

The claim that there is a significant difference between high fructose corn syrup and cane sugar is not supported by the chemical composition of the two substances. Chemically, they are nearly identical, with the only difference being the bond between the glucose and fructose molecules. Studies have shown that both high fructose corn syrup and cane sugar metabolize in the same way in the body, leading to similar health effects. Industry-funded research by companies like Coca-Cola may claim that cane sugar is healthier, but these studies should be viewed skeptically. Independent research has demonstrated the negative health effects of fructose, regardless of the source, and its contribution to metabolic syndrome and fatty liver disease. The claim that honey is different from cane sugar and high fructose corn syrup is also misleading. While honey does contain other nutrients and minerals, its fructose content can still lead to the same negative health effects associated with excess fructose consumption.

The Role of Carbohydrates in Insulin Resistance

01:20

Carnivore Essentials

01:20

Evaluating studies: Comparing evidence and methods

01:00

Introduction

2min

The Role of Cortisol in Ketosis and Weight Loss Struggles

15min

Effects of Carbohydrate-Restricted Diet on Body Composition and Hormone Responses

21min

The Influence of Industry-Funded Research and the Health Effects of Sugar

6min

Reflecting on a Hypothetical Business Model and Choosing Healthier Lifestyle

2min

Comparing High Fructose Corn Syrup and Cane Sugar

15min

The Influence of Paid Content on Social Media Platforms

14min

The Glucose Cortisol Link and Adaptation to a Ketogenic Diet

16min

The Effect of a Ketogenic Carnival Lifestyle on Insulin Sensitivity

28min

10.

Diet and Lifestyle for Anxiety and Cholesterol

10min

11.

Information on Where to Find the Hosts and an Ad for the Bakers Store

2min

In this in episode of the Plant Free MD with Dr Anthony Chaffee, I welcome back my friend Richard Smith (Keto-pro) to do a deep dive into the recent claims that long-term ketosis is harmful to one's health. This came on the back of an interview with Giorgi Dinkov on the Dr Mercola podcast, discussing the potential harms from being on a ketogenic diet, like Carnivore. Richard and I took a look at the evidence presented and offered counter arguments and evidence to show the opposing side of the argument.

Obviously, we are just responding to his podcast without Giorgi being able to respond, so take that as you will, but happily enough Giorgi and I had a friendly debate on the Brian Gryn podcast (below) that you can watch to see both sides in real time.

Giorgi is a very intelligent and well-read individual, and his arguments need to be taken seriously, which is what I hope we have done here. Let me know in the comments which argument you found the most compelling!

Dr Chaffee and Giorgi Dinkov friendly debate on ketogenic diets https://youtu.be/k_LFfSyUADQ

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This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

#weightloss #nutrition #keto #carnivore #fyp #diabetes #cortisol

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The Plant Free MD with Dr Anthony Chaffee

Episode 149: Is Being In Ketosis Harmful Long-term? Here's The Evidence

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

Deep dives

The Similarities Between High Fructose Corn Syrup and Cane Sugar

The Impact of Honey on Glycemic Control

Questioning the Claims About Fructose

Evaluating Claims Based on Context and Experimental Design

The Inaccurate Understanding of Cancer Metabolism

The Effectiveness of Ketogenic Diets in Cancer Treatment

Misunderstanding of Propranolol and its Role in Cancer Treatment

Effect of Ketogenic Diet on Type 2 Diabetes

Cholesterol Misconceptions and Health Benefits of a Ketogenic Diet

The Role of Carbohydrates in Insulin Resistance

Carnivore Essentials

Evaluating studies: Comparing evidence and methods

Remember Everything You Learn from Podcasts