Masters of Scale Inside one of the world’s greatest fundraising operations
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Aug 7, 2025 
Rick Shadyac Jr., the recently retired CEO of ALSAC, shares insights on transforming fundraising for St. Jude Children’s Research Hospital, boosting annual revenue from $600 million to nearly $3 billion. He discusses innovative campaigns, like a space mission featuring former patients, and the importance of data-driven strategies for engaging donors. Shadyac highlights how unique partnerships have fueled significant donations, showcasing the intersection of philanthropy and exploration while emphasizing ongoing investments in childhood cancer research.
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Space Mission Inspires Donations
- Rick Shadyac Jr. shared the intense experience of watching a St. Jude patient launch into space to inspire donations.
- This space mission was a unique media effort that helped raise attention and donations for St. Jude.
Data Drives Fundraising Strategy
- Data storytelling guided St. Jude's strategic investments in diverse media channels.
- Meeting audiences on platforms like TikTok, Instagram, and CNN maximized fundraising reach.
St. Jude’s Unique Mission
- St. Jude offers free cancer treatment, housing, and food; no family receives a bill.
- ALSAC raises about 89% of St. Jude’s operating funds and was founded by Danny Thomas, whose pledge led to the hospital's creation.