Dr. Sofiya Milman, an expert in longevity studies, and Sally Froelich, a vibrant 95-year-old participant, share insights on what defines 'SuperAgers.' They explore genetic factors and lifestyle choices that contribute to remarkable longevity. Sally recounts her uplifting experiences maintaining cognitive health, emphasizing the joys of family life. The conversation also dives into potential interventions for healthier aging and encourages the importance of social connections and happiness for a fulfilling life as we age.
Research into 'SuperAgers' reveals a blend of genetic and lifestyle factors that contribute to their exceptional longevity and health.
The study aims to translate findings from superagers into potential treatments, focusing on early interventions to enhance aging outcomes for all.
Deep dives
Understanding Superagers
Superagers are defined as individuals who reach the age of 95 or older while maintaining intact cognitive function, often living independently. The research aims to study 10,000 superagers to determine the factors contributing to their longevity and healthy aging. This includes understanding their unique experiences and daily lifestyles, which could provide insights into the secrets of living longer, healthier lives. One participant, Sally, expressed her curiosity about the study, emphasizing her interest in reflecting on her life and health as part of the research process.
Genetics vs. Lifestyle
The discussion highlights the balance between genetics and environmental factors in achieving longevity, suggesting that genetics plays a significant role in maintaining health as people age. While lifestyle choices such as exercise, sleep, and stress management are essential, they alone may not account for the extraordinary health of superagers. It has been observed that these individuals often delay the onset of age-related diseases like cancer, Alzheimer’s, and heart disease, indicating a genetic advantage that allows them to thrive well into old age. The researchers are particularly interested in genetic variations that might shield superagers from cognitive decline.
Future Research Directions
Ongoing research aims to translate the findings about superagers into potential treatments that can enhance longevity and health outcomes for the wider population. Scientists are looking at genetic markers and risk factors that can help identify when individuals might benefit from interventions to delay aging and disease onset. A key focus is determining the right timing for treatment, as early intervention could prove crucial before any diseases manifest significantly. By understanding the mechanisms behind superagers' health, researchers hope to create medications that mimic the characteristics of protective genes to aid others in achieving a longer, healthier life.
A common worry among older adults is how their brains and bodies might decline as they age.
A small but fortunate group will live past their 95th birthdays, while staying cognitively sharp and free of major health complications. They’re called “SuperAgers.”
Researchers are working to figure out some of the genetic factors behind SuperAgers’ longevity—and how that knowledge might help the rest of the population live longer and healthier lives.
Ira talks with Dr. Sofiya Milman, director of Human Longevity Studies at Albert Einstein College of Medicine and the lead researcher of the SuperAgers Family Study; and one of the study’s participants, Sally Froelich, a 95-year-old New York resident.
Transcript for this segment will be available after the show airs on sciencefriday.com.