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Dhru Purohit Show

Is Exercise the Miracle Drug We’ve Been Waiting For? The Number One Way to Strengthen Your Mind and Fight Depression with Dr. Nicholas Fabiano

Mar 26, 2025
Dr. Nicholas Fabiano, a psychiatry resident at the University of Ottawa, dives into the transformative power of exercise in treating depression. He introduces the FITT protocol for prescribing physical activity while highlighting the disconnect between healthcare providers and patients on this topic. Their conversation reveals how exercise enhances brain chemistry, combats loneliness, and works effectively alongside medication. Dr. Fabiano also shares insights on creatine's potential in brain health and emphasizes a holistic approach incorporating diet and sleep into mental wellness.
01:14:54

Podcast summary created with Snipd AI

Quick takeaways

  • Exercise has been shown to be as effective as medication for treating mild to moderate depression by enhancing neurotransmitter levels.
  • The FITT protocol provides a structured approach for prescribing exercise, emphasizing frequency, intensity, type, and time to maximize benefits.

Deep dives

Exercise as an Effective Antidepressant

Exercise has emerged as a powerful tool for treating depression, comparable in effectiveness to talk therapy and medication. Recent research indicates that regular physical activity can lead to significant improvements in mental health, by increasing levels of key neurotransmitters like serotonin, norepinephrine, and dopamine. In Canada, exercise is even recommended as a first-line treatment in clinical guidelines, yet many healthcare providers and patients remain unaware of its full potential. Educating both patients and medical practitioners about the benefits of exercise in managing depression is crucial for bridging the existing gap in treatment options.

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