

STUBBORN BODY FAT DIFFERENCES BETWEEN MEN & WOMEN: SEX DIFFERENCES SERIES PART 2 | EP. 158
Apr 17, 2025
Discover how stubborn body fat varies between men and women due to biological factors. Learn why certain areas are harder to lose fat from, with insights into alpha and beta adrenergic receptors’ roles in fat breakdown. Explore the science behind catecholamines and their effects on fat loss. Understand how hormonal differences influence fat storage, and see how blood flow impacts lipolysis. This deep dive into the mechanisms of stubborn fat will change how you think about body composition!
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Coach's Personal Stubborn-Fat Story
- Brandon DeCruz shares his personal struggle with stubborn lower back fat that only disappeared at stage condition.
- He uses bodybuilding competition experience to illustrate how deep dieting removes stubborn areas.
Fat Loss Happens Top-Down And Inside-Out
- Stubborn fat is common and often the last to go during dieting, with arms and face leaning out first.
- You must reach deeper body-fat levels and consistent deficit to tap into those stubborn regions.
Adrenergic Receptor Balance Controls Lipolysis
- Beta-2 receptors stimulate lipolysis while alpha-2 receptors inhibit it, creating opposing effects on fat mobilization.
- The local balance of these receptors determines how easily fat leaves a given region.