ZOE Science & Nutrition Recap: Tips to help prevent Alzheimer’s | Drs. Ayesha & Dean Sherzai
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Dec 16, 2025 
Drs. Ayesha and Dean Sherzai, expert neurologists specializing in brain health, delve into the rising rates of Alzheimer’s and the vital role lifestyle choices play in prevention. They introduce their NEURO framework focusing on nutrition, exercise, stress relief, restorative sleep, and cognitive engagement. Emphasizing plant-forward diets like MIND and Mediterranean, they highlight the crucial benefits of key nutrients such as B12, vitamin D, and omega-3s, showing how simple dietary changes can significantly reduce Alzheimer’s risk.
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NEURO Connects Lifelong Habits To Dementia Risk
- The Sherzais' NEURO plan links lifelong lifestyle factors to Alzheimer's risk across nutrition, exercise, stress, sleep, and cognitive activity.
- These factors interact over decades to increase or reduce dementia risk, so early and sustained changes matter.
Brain Is Highly Metabolic And Vascular
- The brain uses 25% of the body's energy and has an extensive vascular network, so metabolic and vascular health strongly affect cognition.
- Anything that harms heart, gut, or metabolic health will likely impact the brain even more intensely.
Brain Health Is Whole‑Body Health
- The brain is not isolated; what affects other organs also affects the brain and often more so.
- Viewing brain health as integrated with overall health clarifies why broad lifestyle habits matter.