Heart Doc VIP with Dr. Joel Kahn

Episode 426: How the TRANSFORM Study Could Change Heart Disease Prevention

10 snips
Apr 8, 2025
Discover groundbreaking insights from the TRANSFORM Study, which could revolutionize heart disease prevention. Explore the importance of Lipoprotein(a) and coronary calcium scoring in assessing heart health risks. Dive into the health and environmental benefits of plant-based diets and nutritious smoothies. Learn about the potential risks of gadolinium-based contrast in MRI scans. This enlightening discussion emphasizes the need for early detection and innovative care strategies in combating cardiovascular issues.
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ADVICE

Dihydroberberine-SR for Metabolic and Cardiovascular Health

  • Try dihydroberberine-SR, a sustained-release form of berberine, to support glucose balance, lipid metabolism, and cardiovascular health.
  • Take 150 milligrams twice daily; it's vegan, gluten-free, and activates the AMPK pathway, similar to metformin.
INSIGHT

Lepodicerine Reduces Lipoprotein(a)

  • A new drug, lepodicerine, significantly reduces lipoprotein(a) levels, showing promise in early trials.
  • Headlines misrepresented the study; it didn't measure heart attacks or death, only lipoprotein(a) reduction.
INSIGHT

Lipoprotein(a) and Calcium Score

  • A study of over 44,000 people found that high lipoprotein(a) alone doesn't significantly increase heart disease risk if the calcium score is zero.
  • This suggests a less aggressive treatment approach may be warranted in these cases.
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