The Dr. Hyman Show Are You Nutrient Deficient? The Hidden Factors of Accelerated Aging | Rhonda Patrick - ENCORE
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Dec 31, 2025 
Dr. Rhonda Patrick, a renowned biomedical scientist and advocate for longevity, discusses the critical impact of micronutrient deficiencies on health and aging. She explains the essential roles of vitamin D, magnesium, and omega-3s in longevity and cognitive function. Rhonda also critiques the flaws in nutrition trials and emphasizes the importance of personalized micronutrient intake. With practical tips on enhancing your diet and supplement strategies, she empowers listeners to prioritize their nutrient needs for better health and aging.
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Triage Theory Explains Nutrient Allocation
- Bruce Ames' triage theory explains the body prioritizes short-term survival functions over long-term maintenance when nutrients are scarce.
- This rerouting leaves DNA repair and longevity pathways undermined, accelerating age-related diseases.
Meeting Bruce Ames Shaped Her Career
- Rhonda Patrick described meeting Bruce Ames who encouraged her public science communication and research on micronutrients.
- His mentorship steered her toward studying aging, DNA repair, and nutrient biology.
Folate Shortage Directly Damages DNA
- Folate deficiency causes uracil misincorporation and double-stranded DNA breaks, linking micronutrient insufficiency to cancer risk.
- Restoring folate corrected DNA damage in rodent and human studies, showing nutrient causality in genome maintenance.