Kevin White, a former ICU nurse at Mayo Clinic, and Erik Nelson, a lifestyle intervention expert, team up for an enlightening discussion on cognitive decline. They unveil a multi-faceted program aimed at halting and even reversing cognitive decline, emphasizing the importance of personalized diagnostics like blood tests and brain scans. They dive into advanced therapies including rapamycin and peptides, while also sharing lifestyle interventions as 'brain armor.' This insightful conversation challenges traditional views and offers hope for new strategies against dementia.
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Early Concussions Sparked A Brain-Focused Career
Kevin White describes childhood exposure to neurosurgery and multiple concussions from football that shaped his interest in brain health.
He links those injuries and family background to his later clinical focus on cognitive decline prevention.
insights INSIGHT
Plaques Are Part Of A Bigger Puzzle
Matt Kaeberlein argues amyloid plaque targeting is incomplete and likely insufficient to stop dementia progression.
He suggests plaques may be a response rather than the single cause of neurodegeneration.
volunteer_activism ADVICE
Test Early And Monitor Longitudinally
Run targeted diagnostics (genetics, P‑tau, NFL, MRI, cognitive tests) to reveal early pathology and personalize interventions.
Use longitudinal monitoring to keep plaque stable and prevent rises in neurofilament light that signal cell death.
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Subscribe to our channel: https://www.youtube.com/@optispanGet Our Newsletter (It's Free): https://www.optispan.life/Today Dr. Kevin White and Erik Nelson join us for a deep-dive conversation as they unveil a new, multi-faceted program designed to halt and even reverse cognitive decline. They break down the key diagnostics, lifestyle pillars, and advanced therapies that form the foundation of their science-backed blueprint for brain health.0:00 - The Mission: Why We're Tackling Dementia16:14 - The Diagnostic Blueprint: Blood, Brain Scans & Cognitive Tests40:44 - The Foundation: Lifestyle as Brain Armor49:28 - Level 1: The Core Supplements for Brain Health56:59 - Level 2: Game-Changing Medications (Rapamycin & More)1:12:47 - Level 3: The Experimental Frontier (TPE, Sauna & Peptides)1:23:24 - The Program Unveiled: Who It's For & How It WorksProduction: Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://x.com/Optispan_IncTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispan_/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!
The Optispan Podcast with Matt Kaeberlein