
Wild Health Podcast
The Science of Staying Young: Senolytics Explained by Dr. Gregory Kelly!
May 22, 2024
Dr. Gregory Kelly discusses cellular senescence and senolytics in the Wild Health Podcast. Topics include the impact of senescent cells on health, evolution of senolytics, mechanisms of senolytics, practical insights on usage, and the creation of Qualia Senolytic supplement for enhanced wellness.
45:22
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Quick takeaways
- Cellular senescence leads to altered gene expression and damage accumulation, affecting aging progression.
- Senolytics target and eliminate senescent cells, offering potential to improve tissue function and combat aging.
Deep dives
Understanding Cellular Senescence and its Impact on Aging
Cellular senescence occurs when cells can no longer divide and replace themselves due to profound cellular stress, leading to resistance to apoptosis. This process is considered a hallmark of aging, contributing to damage accumulation and altered gene expression as we age. Senescent cells secrete molecules into the environment, affecting nearby healthy cells and potentially accelerating aging.
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