Brain Inspired

BI 121 Mac Shine: Systems Neurobiology

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Dec 2, 2021
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INSIGHT

Holistic Brain Function

  • Mac Shine emphasizes the importance of a holistic approach to understanding the brain, challenging the cortico-centric view.
  • He highlights the thalamus's crucial role, not merely as a relay, but as a dynamic state controller influenced by various brain regions.
INSIGHT

Matrix Cell Projection

  • Matrix cells in the thalamus, unlike core cells, project diffusely, impacting broader brain regions.
  • This diffuse projection acts like temperature, increasing the likelihood of contacted areas joining active coalitions, enhancing flexibility.
ANECDOTE

Effortless Walking

  • Mac Shine's father, an evolutionary biologist, observed a shift in his grandson's walking from effortful to effortless.
  • This prompted Mac to consider the cerebellum's role in automating learned behaviors, leading to effortless execution.
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