

The Actual Reason Men Die First
18 snips Aug 26, 2025
Why do men have a shorter life expectancy than women? The discussion dives into genetic and lifestyle factors, highlighting the crucial role of the FOXO3 gene. Listeners will uncover key strategies to boost longevity, along with eight actionable tips to increase life expectancy for everyone. The conversation reveals essential longevity risk factors to avoid, paving the way for healthier living.
AI Snips
Chapters
Transcript
Episode notes
FOXO3 Explains Female Longevity
- The FOXO3 longevity gene helps with stress resistance, DNA repair, and cancer prevention.
- Women express FOXO3 more due to estrogen, which likely explains part of their longer lifespan.
Evolutionary Reason For Sex Gap
- Evolution favored stronger protection for women due to reproduction, leading to greater FOXO3 expression.
- This reproductive advantage contributes to observed sex differences in lifespan.
Use Phytonutrients To Activate FOXO3
- Consume phytonutrient-rich foods like salmon (astaxanthin) and cruciferous vegetables for sulforaphane.
- These compounds activate FOXO3 and offer antioxidant and cellular protection.