The Curbsiders Internal Medicine Podcast

#92: Pulmonary Embolism for the Internist

Apr 23, 2018
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INSIGHT

PE and DVT Relationship

  • Pulmonary embolisms (PEs) originate from deep vein thromboses (DVTs).
  • Treat DVTs to prevent PE development, as PEs pose a greater mortality risk.
INSIGHT

PE Pathophysiology

  • Increased clot burden exponentially raises pulmonary vascular resistance, straining the right ventricle (RV).
  • RV failure can cause systemic hypotension due to decreased left ventricle output.
INSIGHT

RV Ischemia in PE

  • Right ventricle (RV) ischemia, caused by reduced coronary perfusion during RV failure, can lead to a fatal death spiral.
  • Focus on hemodynamic manifestations of PE, like RV dysfunction and hypotension.
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