Science Weekly
Summer picks: what can our dogs teach us about obesity?
Aug 27, 2024
In this engaging discussion, Dr. Eleanor Raffan, a researcher focused on genetic influences on obesity, teams up with Prof. Giles Yeo, an expert in metabolic diseases, to explore the fascinating connection between canine and human obesity. They dive into how a genetic mutation in Labradors affects their eating behavior and what this reveals about human weight struggles. The conversation highlights the significant role of genetics and environment in obesity, challenging the idea that it's merely a matter of personal choice, and offers valuable insights for managing health.
20:44
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Quick takeaways
- Genetic variants in dogs, especially Labradors, reveal insights into obesity, highlighting the impact of genes on hunger and fullness signals.
- Both genetic predispositions and environmental factors play crucial roles in managing obesity in dogs and humans, emphasizing the need for systemic dietary changes.
Deep dives
Genetic Factors in Canine Obesity
Certain dog breeds, particularly Labradors and flat-coated retrievers, exhibit a genetic variant in the POMC gene that appears to contribute to obesity. This mutation affects the brain's processing of hunger and fullness signals, making these dogs more likely to overeat. Research reveals that about a quarter of Labradors possess this variant, with a higher prevalence in guide dogs, which may indicate a selection for more food-motivated traits in working environments. Understanding this genetic influence helps explain why some dogs are more prone to weight gain, offering insights into obesity's complexities in both pets and humans.
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