Nutrition Facts with Dr. Greger

Is Longevity Genetic?

7 snips
Jun 13, 2024
Uncover the link between genetics and longevity with insights on heritability and lifestyle choices, the impact of genes on Alzheimer's disease, and how diet can counter genetic predispositions for better health and longer life.
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INSIGHT

Moderate Genetic Role in Longevity

  • Longevity heritability based on twin studies is about 25%, showing genetics have a moderate role.
  • How we live our lives likely influences the majority of our lifespan beyond genetics.
INSIGHT

Nine Hallmarks Define Aging

  • Aging is defined by nine hallmarks that include DNA damage, telomere shortening, and inflammation.
  • These aging mechanisms form targets for potential anti-aging interventions.
INSIGHT

ApoE Gene Dominates Longevity

  • The ApoE gene is the key genetic factor linked to longevity across multiple studies.
  • ApoE variants significantly impact dementia risk and overall lifespan.
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