Huberman Lab

How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its Risks

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May 8, 2023
Explore the fascinating world of psilocybin and its impact on the brain. Discover how this compound triggers neuroplasticity, leading to potential therapeutic benefits for depression and addictions. Learn about the different dosages and the significance of set and setting during a psilocybin experience. The discussion also highlights which groups may be at risk and the evolving legal landscape surrounding its use. This in-depth look provides valuable insights for anyone curious about psychedelics and mental health.
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INSIGHT

Psilocybin and Serotonin

  • Psilocybin mimics serotonin, activating specific serotonin receptors strongly.
  • This triggers neuroplasticity, causing lasting emotional and cognitive shifts.
INSIGHT

Therapeutic Neuroplasticity

  • Neuroplasticity from psilocybin isn't always therapeutic; it must be adaptive.
  • Therapeutic neuroplasticity improves life function, requiring specific conditions.
ADVICE

Legality and Safety

  • Psilocybin remains a Schedule I drug, illegal except in specific settings.
  • Exercise caution and consult a physician before considering psilocybin use.
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