AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
More Plates More Dates
$25,000 Follistatin Gene Therapy - Before & After Results Analysis With Peter Attia
Jan 2, 2025
In this engaging conversation, Peter Attia, a renowned physician and researcher focused on longevity, dives into the groundbreaking world of gene therapy targeting follistatin. He explains how inhibiting myostatin could revolutionize muscle growth but warns of the hype surrounding its commercialization. The discussion sheds light on the often misleading practices in fitness photography and critiques inflated claims of gene therapy results. Attia emphasizes the importance of scientific validation, especially regarding the unexpected metabolic effects observed in users.
18:54
Episode guests
AI Summary
AI Chapters
Episode notes
Podcast summary created with Snipd AI
Quick takeaways
- Follistatin gene therapy has potential for muscle growth by inhibiting myostatin, yet its human clinical efficacy remains uncertain and costly.
- The rise of unregulated folistatin products lacks scientific backing, often resulting in disappointing results and highlighting the need for FDA approval.
Deep dives
Gene Therapy and Myostatin Inhibition
Gene therapy targeting myostatin inhibition involves the introduction of a vector that activates the gene for folistatin, a protein that restrains myostatin, potentially leading to increased muscle growth. Myostatin plays a significant role in regulating muscle mass, and studies have shown that myostatin knockout mice exhibit a striking double muscle phenotype. Researchers discuss an emerging gene therapy treatment priced at $25,000 per shot, which aims to enhance folistatin levels and theoretically reduce myostatin's effects in humans. However, while animal studies suggest promise, the clinical results in humans remain uncertain, leading to questions about the efficacy and realism of such treatments in achieving substantial muscle gain.
Get the Snipd
podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any
moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share
& Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode