The Gillett Health Podcast Correcting TRT Advice
4 snips
Jun 25, 2024 
Expert Peter Attia discusses testosterone replacement therapy in detail, covering steady state testosterone, appropriate TRT usage, and the risks involved. They dive into the implications of TRT on prostate cancer, cardiovascular disease, dosage differences, and risks of obtaining TRT illegally. The conversation also explores the impact of TRT on fertility, long-term endogenous testosterone production, and the use of alternative methods like clomiphene and enclomiphene.
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Physiological vs. Non-Physiological TRT
- Any steady-state TRT is non-physiologic, differing from natural testosterone fluctuations.
- Subcutaneous TRT is also non-physiologic, not just super-physiologic doses.
Black Market TRT Source
- Most black market TRT is diverted from legitimate prescriptions, not bathtub labs.
- Actual black market substances are more likely other compounds, not testosterone.
TRT and Prostate Cancer
- TRT does not initiate prostate cancer, but it can fuel existing prostate cancer.
- Monitor PSA levels closely, especially after a prostatectomy, and cease TRT if cancer recurs.