
Making Space with Hoda Kotb Dr. Mindy Pelz on the Wisdom That Emerges from Menopause
Jan 14, 2026
Dr. Mindy Pelz, a New York Times bestselling author and women's health expert, dives into the transformative experience of menopause. She reframes menopause from a decline to a purposeful evolution, discussing how estrogen loss can foster brain growth and authentic introspection. Mindy shares practical lifestyle strategies to combat brain fog and improve memory, emphasizing the role of nutrition and fasting. She offers hope that menopause can lead to intentional living and encourages personalized approaches to hormone replacement therapy.
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Brain Remodels During Menopause
- Menopause triggers a purposeful brain remodel rather than an inevitable decline.
- Neurons linked to people-pleasing are shed while introspective circuits grow, enabling new priorities.
Less People‑Pleasing, More Inner Voice
- The brain sheds neurons that reinforced external validation and builds ones that support inner voice.
- This biological shift explains why many women stop caring what others think and speak their truth.
Use Lifestyle To Ease The Ten‑Year Remodel
- Use lifestyle tools to influence your brain chemistry during the 10-year remodel.
- Prioritize calming environments and social connection to lower cortisol and improve insulin sensitivity.




