The Liz Moody Podcast

GLP-1s: The New Science Transforming Hormones, Weight Loss, Brain Health, and Beyond

Oct 22, 2025
Dr. Rocio Salas-Whalen, a board-certified endocrinologist and obesity medicine specialist, delves into the surprising benefits of GLP-1 medications beyond appetite suppression. She discusses their impact on fertility, inflammation, and even addictive behaviors, reshaping our understanding of metabolic and hormonal health. Dr. Salas-Whalen emphasizes the importance of body composition over BMI and shares insights on how muscle serves as an anti-inflammatory powerhouse. Get ready for a mind-opening conversation on holistic health and the future of weight management!
Ask episode
AI Snips
Chapters
Books
Transcript
Episode notes
INSIGHT

GLP-1s Rewire Reward And Craving

  • GLP-1s alter the brain's reward system, reducing the anticipated reward from substances like alcohol and some drugs.
  • That reduced reward weakens habit loops so cravings and future wanting decline over time.
ADVICE

Treat PCOS By Targeting Insulin First

  • Use GLP-1 medications to target insulin resistance and hyperinsulinemia in PCOS for better outcomes than metformin.
  • Discuss GLP-1s with your clinician as a primary treatment option if PCOS and metabolic dysfunction drive symptoms.
INSIGHT

Anti-Inflammatory Effects Reduce Autoimmunity

  • GLP-1s have indirect and some direct anti-inflammatory effects that can improve fertility and autoimmune symptoms.
  • Early reductions in pro-inflammatory food intake often relieve swelling and joint symptoms before weight loss occurs.
Get the Snipd Podcast app to discover more snips from this episode
Get the app