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Big Brains

Why We Die—And How We Can Live Longer, with Nobel Laureate Venki Ramakrishnan

Apr 18, 2024
Nobel Laureate Venki Ramakrishnan discusses aging, immortality, and the $30 billion longevity industry. Topics include DNA damage, telomeres, caloric restriction, stem cell reprogramming, and ethical considerations in anti-aging advancements.
32:31

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Quick takeaways

  • Understanding DNA damage and repair responses is crucial in unraveling the mystery of aging.
  • Cellular reprogramming offers potential in rejuvenating stem cells for tissue regeneration and longevity.

Deep dives

Understanding Aging and Longevity Research

Aging has long been a mystery, with lifespans varying widely across species. The reasons behind aging involve a complex interplay of multiple factors, including DNA damage and repair responses. Environmental factors and natural processes constantly affect our DNA, leading to changes and errors in protein production over time. Researchers are exploring DNA methylation as a potential indicator of aging and investigating how reversing methylation patterns could affect the aging process.

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