

The Powerful Alternative To The Addictive Nicotine Pouch Craze with Matt Wan from Sett
Aug 12, 2025
Matt Wan, founder of Sett and Momentus, dives into the enticing world of nicotine alternatives. He reveals how Sett combines seratine and L-theanine for a smoother experience without the addiction. The conversation unpacks the stark differences between nicotine and tobacco, the innovative formulation behind Sett, and user experiences. Matt emphasizes the importance of small successes in health changes and explores the exciting future of health products, including healthier alternatives approaching nicotine dependence.
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Seratine Acts Like Nicotine Without Same Dependence
- Seratine binds nicotinic acetylcholine receptors similarly to nicotine but spares the alpha-6 subtype linked to strong physical dependence.
- That receptor profile suggests nicotine-like cognitive effects with potentially lower addiction risk.
Sean's First Impressions: Gentler And Effective
- Sean tried SET and reported he liked it more than expected, praising the wintergreen mouthfeel and gentle effect.
- He described the effect as slower uptake with a long plateau and less edginess than nicotine pouches.
Combine L-Theanine To Smooth Effects
- Combine active ingredients to offset side effects when tobacco regulation prevents formulation adjustments.
- Use L-theanine with seratine to reduce vasoconstriction and withdrawal symptoms while smoothing the experience.