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Paul Saladino MD podcast

242. Debunking Cholesterol Myths: New Study Reveals Surprising Findings! With Dave Feldman

Dec 19, 2023
Dave Feldman, a researcher studying LDL and cardiovascular risk, joins Paul Saladino on the podcast. They discuss a recent study about LDL and cardiovascular risk, the response from the medical community, and the role of credentials in online discussions. They also explore the risks and benefits of lipid-lowering therapies like statins and the effects of ketogenic and low carb diets on LDL cholesterol levels.
01:13:58

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Quick takeaways

  • Lean individuals with elevated LDL and ApoB levels may not have the same risk of cardiovascular disease as the general population.
  • FH and lean mass hyper-responders, both with high LDL, are not the same and have differences in macrophage function and genetics.

Deep dives

The Study on Lean Mass Hyper-responders

A study is conducted on a unique population of lean individuals with significantly elevated LDL and ApoB levels. The purpose of the study is to determine whether these individuals, who are metabolically healthy, have the same increased risk of cardiovascular disease and plaque formation as the general population.

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