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32min chapter
242. Debunking Cholesterol Myths: New Study Reveals Surprising Findings! With Dave Feldman
Paul Saladino MD podcast
The Differences Between Familial Hypercholesterolemia and Lean Mass Hyper Responders
This chapter explores the immunologic differences between individuals with familial hypercholesterolemia (FH) and lean mass hyper responders, highlighting why FH is not a good model system. It also discusses the relationship between lipid metabolism and the immune response, particularly in the context of macrophages and atherosclerosis. The chapter showcases a study that examines physically different macrophages in individuals with monogenetic FH and discusses the potential benefits of lipid-lowering therapy for those with FH.
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