The Energy Blueprint Podcast Dr. Scott Sherr: Methylene Blue, GABA, and the Hidden Link Between Mitochondria and Stress
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Jul 26, 2025 
Dr. Scott Sherr, a board-certified internal medicine physician and hyperbaric oxygen therapy specialist, dives into the surprising link between mitochondria and stress. He reveals that 94% of US adults experience mitochondrial dysfunction and how chronic stress depletes GABA, the brain's calming neurotransmitter. Scott discusses the meteoric rise of methylene blue, its potential benefits, and how GABA deficiency can mimic anxiety and depression. He emphasizes the importance of shifting the nervous system for healing and offers practical tips for managing stress.
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Methylene Blue's Unique Role
- Methylene blue is a long-known compound that enhances mitochondrial function and acts as a profound antimicrobial agent.
- It bypasses dysfunctional mitochondrial complexes, offering energy and detox support without harming human cells.
Widespread Mitochondrial Dysfunction
- About 94% of U.S. adults have mitochondrial dysfunction affecting energy production.
- Methylene blue can help bypass these dysfunctions, improving energy and supporting health even in non-inherited cases.
Calm Your Nervous System
- Prioritize downregulating sympathetic dominance to enable healing and improve nervous system balance.
- Practices like breathwork, meditation, yoga, and reducing chronic stress are essential for recovery.