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Immuno-Oncology and Immune Balance
- Immuno-oncology harnesses the immune system to fight cancer by turning it on or redirecting it.
- The immune system can be too hot (autoimmune disease) or too cold (cancer ignoring), requiring precise modulation.
Precision Targeting in Cancer Therapy
- Targeted drug delivery can improve potency and reduce toxicity by hitting only cancer cells.
- Current chemotherapy hits rapidly dividing cells non-selectively, causing harmful side effects.
Antibodies Redirect Immune System
- Antibodies serve as 'flags' that recognize cancer cells, enabling immune cells to be redirected.
- CAR T cells and T cell engaging biologics use antibodies to bridge and activate immune cells against tumors.