High Performance Health

The 5-Minute Workout That Boosts VO₂ Max, Brain Health & Longevity | Ulrich Dempfle

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Oct 19, 2025
Ulrich Dempfle, co-founder and CEO of CAROL Bike, shares insights on Reduced-Exertion High-Intensity Interval Training (REHIT). He explains how just a few minutes of AI-personalized sprints can significantly boost VO₂ max, which is a crucial marker for longevity. Dempfle debunks myths about traditional zone 2 training, highlighting its ineffectiveness for some. He also discusses the cognitive benefits of REHIT, particularly its impact on brain health through increased BDNF and insulin sensitivity.
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INSIGHT

VO2 Max Predicts Longevity

  • VO2 max is the strongest predictor of longevity and declines ~10–12% per decade after age 30.
  • Improving VO2 max reverses biological aging and restores capacity in minutes per week with the right stimulus.
INSIGHT

Zone 2 Is Not A Universal Fix

  • Zone 2 training helps some people but ~40% are low responders and may see no VO2 max gain.
  • Prescribing hours of zone 2 for the general public is inefficient and often ineffective.
INSIGHT

Two Ways To Improve Mitochondria

  • Mitochondrial health has two dimensions: density (number/size) and efficiency (how well they work).
  • Different exercise intensities preferentially target density versus efficiency, so you want both.
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