#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle
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Nov 27, 2024
Explore the surprising importance of protein beyond muscle building. Discover how higher protein intake supports metabolic health, longevity, and decreases risks of type 2 diabetes and sarcopenia. The conversation challenges the traditional RDA, advocating for increased consumption, especially for those training. Delve into the myths of the anabolic window and proper protein timing. Additionally, find out how exercise can influence protein's relationship with cancer and heart health, while keeping kidneys safe.
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insights INSIGHT
Muscle Loss and Aging
Muscle mass is a better indicator of aging than body weight or BMI.
After age 50, people lose 1% of muscle mass yearly, and strength declines even faster.
insights INSIGHT
Anabolic Resistance
Anabolic resistance, reduced muscle responsiveness to amino acids, is a key factor in age-related muscle loss.
Physical inactivity significantly contributes to anabolic resistance.
volunteer_activism ADVICE
Combating Anabolic Resistance
Combat anabolic resistance with regular exercise and higher protein intake (around 1.6g/kg).
Building muscle is possible even in older age.
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Protein is far more than a building block for muscle—it’s essential for metabolic health, insulin sensitivity, and preventing conditions like type 2 diabetes and sarcopenia. But how much do we truly need? And could too much protein, especially from meat, actually be harmful? This episode challenges the conventional RDA of 0.8 g/kg, presenting research that supports higher intakes of 1.2–2 g/kg for maintaining muscle, improving body composition, and promoting longevity. We also confront myths around protein timing and the so-called "anabolic window.” Lastly, we address concerns about protein’s links to cancer, heart disease, and kidney function, showing how exercise can redirect growth factors like IGF-1 to promote repair while mitigating risks.
Timestamps:
(00:00) Download my “How to Train” guide
(00:51) Introduction
(03:32) Why muscle matters
(05:57) Why do we lose muscle?
(07:31) How to negate anabolic resistance
(08:24) Why it's never too late to build muscle
(09:05) Requirements for overweight & obese individuals
(09:52) Exposing the flaws of the RDA
(11:12) Optimal intake when resistance training
(11:55) What to do when losing weight
(13:08) Does protein harm healthy kidneys?
(14:59) How important is distribution?
(17:11) Debunking the "anabolic window"
(18:48) Benefits of pre-sleep intake
(20:20) Timing & distribution takeaways
(21:01) What are the best sources?
(24:05) Animal vs. plant protein
(26:27) Protein supplements (whey, casein, & collagen)
(27:57) Does high intake accelerate aging?
(31:32) Why exercise changes the story
(34:02) What we can learn from athletes
(34:36) Does high intake accelerate atherosclerosis?
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