

Disease and the Problem of Evil | Prof. Stephen C. Meredith
The Blood of the Lamb
- Peter DeVries's novel "The Blood of the Lamb" tells the story of a young girl with leukemia.
- DeVries blends comedy and theology, offering poignant insights into suffering.
Sylvester's Case
- Sylvester, a 14-year-old with sickle cell anemia, suffered from pain crises and other complications.
- His case highlighted the devastating impact of a single nucleotide mutation.
Sickle Cell Biology
- Sickle cell trait provides malaria resistance but can lead to sickle cell anemia.
- This balanced polymorphism demonstrates a complex biological trade-off.


















Professor Stephen Meredith explores the problem of evil, particularly in the context of disease, examining philosophical and theological perspectives, including those of Aquinas, Leibniz, and Voltaire, while also considering biological factors like genetics and evolution.
This lecture was given on November 7th, 2024, at Indiana University.
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About the Speaker:
Stephen Meredith is a professor at the University of Chicago’s Departments of Pathology, Biochemistry and Molecular Biology, and Neurology. He is also an associate faculty member in the University of Chicago Divinity School. He has published more than 100 journal articles, focusing on the biophysics of protein structure. Much of his work has been the application of solution and solid-state NMR to the study of amyloid proteins associated with neurodegenerative diseases such as Alzheimer’s Disease. He has also published articles on literature and philosophy in diverse aspects of medical humanities and bioethics. His teaching includes courses to graduate students in biochemistry and biophysics, medical students, and undergraduates and graduate students in the humanities, including courses on James Joyce’s Ulysses, St. Thomas Aquinas, Augustine, Dostoevsky (focusing on Brothers Karamazov), Thomas Mann and David Foster Wallace. He is currently working on a book examining disease and the theological problem of evil. Other current writing projects include a study of James Joyce and the problem of evil.
Keywords: Boethius, Disease, Evil, Leibniz, Original Sin, Problem of Evil, Sickle Cell Anemia, Theodicy, Thomas Aquinas, Voltaire