The Proof with Simon Hill

Does Keto Accelerate Heart Disease? What the New Study Didn’t Tell You | Simon Hill, Msc, Bsc

12 snips
Jun 24, 2025
Guest
Alan Flanagan
Dr. Alan Flanagan, a medical expert and co-author of a critical analysis on the Keto CTA study, joins the discussion to unpack its controversial findings. They explore what Lean Mass Hyper-Responders are and why the study lacks real trial parameters. The conversation delves into the significance of non-calcified plaque volume and questions the role of ApoB in heart disease. Flanagan emphasizes how misleading headlines can skew public perception of keto diets, offering crucial insights for those navigating cardiovascular risks.
Ask episode
AI Snips
Chapters
Books
Transcript
Episode notes
INSIGHT

Keto Study Tracks Plaque Progression

  • The Keto-CTA study observed lean, metabolically healthy keto dieters with extremely high LDL cholesterol and monitored their arterial plaque progression over 12 months.
  • This unique group showed accelerated plaque growth despite good metabolic health, challenging the notion that high LDL is harmless in keto contexts.
INSIGHT

Critical Plaque Data Omitted

  • The study omitted the primary outcome, change in non-calcified plaque volume, from the published paper and abstract, raising concerns about transparency.
  • Data revealed keto dieters had nearly 4x more plaque progression than healthy controls, indicating accelerated artery damage.
INSIGHT

Keto LDL Elevation Links To Higher Risk

  • Keto dieters' rate of arterial plaque progression resembled or exceeded that seen in intermediate or high cardiovascular risk groups.
  • Labeling these individuals as metabolically healthy is misleading since their plaque progression indicates significant cardiovascular risk.
Get the Snipd Podcast app to discover more snips from this episode
Get the app