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Psychedelic Brain Mechanisms
- Classic psychedelics activate serotonin 2A receptors affecting perception, mood, and thought processes.
- The compounds may increase brain connectivity and turn off the default mode network, relevant to ADHD symptoms like mind wandering.
Historical Psychedelic Research
- Early psychiatric use of psychedelics was to induce psychosis for study, unexpectedly revealing pleasant effects.
- Research showed potential for addiction, depression, anxiety, PTSD, OCD, and end-of-life distress treatment.
James' Profound Psychedelic Insight
- James Brown experienced profound insights about his self-hatred during a macro dose of psychedelics.
- He traced his mental health issues back to childhood rejection and neurodevelopmental delays.