The Exam Room by the Physicians Committee

How a Vegan Diet Could Still Raise Cholesterol | Dr. Kim Williams

Sep 2, 2025
Dr. Kim Williams, a leading cardiologist, shares valuable insights on managing cholesterol even for those on a vegan diet. He explains how saturated fats and ultra-processed foods can impact heart health, despite not containing cholesterol. Williams emphasizes the importance of a high-fiber, whole food, plant-based diet for supporting gut health. He also discusses how public health policies in other countries have successfully reduced heart disease rates. Plus, he offers practical tips for clearer food labeling and healthier eating choices.
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INSIGHT

Microbiome Directly Affects Cholesterol

  • The gut microbiome controls immune response, drug and nutrient absorption, and influences cholesterol handling.
  • A high-fiber, whole-food, plant-based diet promotes bacteria that break down cholesterol in the gut.
ADVICE

Avoid Ultra-Processed Vegan Foods

  • Avoid ultra-processed vegan products high in sugar, refined grains, and saturated fat.
  • Read ingredient lists and check saturated fat, sodium, and sugar-to-fiber ratios to manage cholesterol.
INSIGHT

Saturated Fat Triggers Body To Make Cholesterol

  • Saturated fat stimulates the liver to make more cholesterol, raising blood LDL as if you ate cholesterol itself.
  • Dietary and endogenously made cholesterol both end up in the terminal ileum affecting absorption and levels.
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