PLANTSTRONG Podcast Ep. 278: Dr. Michael Greger - Unpacking Ozempic: Miracle Weight Loss Drug or Just Another Fad?
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Dec 5, 2024 
Dr. Michael Greger, a physician and nutrition expert known for his focus on health through diet, delves into the buzz around Ozempic and similar weight-loss drugs. He critically assesses their risks, benefits, and the science behind appetite control through GLP-1 hormones. Greger questions the sustainability of these medications compared to natural weight-loss methods like a plant-based diet, exercise, and lifestyle changes. He also emphasizes the importance of informed choices, urging listeners to consider safer, long-term alternatives to quick fixes.
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GLP-1 and Satiety
- GLP-1, a digestive hormone, signals satiety to the brain, regulating appetite.
- Nutrient-sensing cells at the end of the digestive tract trigger GLP-1 release, but processed foods interfere with this process.
Gila Monster Venom
- Gila monster venom contains a long-lasting GLP-1 agonist.
- This discovery led to the development of long-acting GLP-1 drugs like Ozempic.
GLP-1 Drug Efficacy
- GLP-1 drugs triple the weight loss of other drugs, about 15% body weight reduction.
- However, weight loss plateaus after a year, requiring lifelong medication.
