STEM-Talk

Episode 178: Karl Herrup discusses the shortcomings of Alzheimer’s research

4 snips
Feb 5, 2025
Dr. Karl Herrup, a neurobiologist and author of 'How Not to Study a Disease: The Story of Alzheimer’s,' delves into the critical flaws of the amyloid cascade hypothesis in Alzheimer’s research. He argues that this longstanding theory may be hindering real progress toward a cure. Joined by Dr. Tommy Wood, they discuss the complexities of diagnosing Alzheimer’s, the roles of DNA damage, and the need for innovative approaches to treatment. Herrup emphasizes the importance of rethinking research methods to better understand this multifaceted disease.
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ANECDOTE

Gifted Peers

  • Karl Herrup's high school classmates were children of Westinghouse engineers and scientists.
  • This environment provided intellectual stimulation during his formative years.
ANECDOTE

From Medicine to Genetics

  • Karl Herrup initially intended to become a physician but changed his mind after taking a genetics course.
  • Chandler Fulton's genetics class inspired him to pursue basic research.
ANECDOTE

Paternal Disapproval

  • Karl Herrup's father was furious with his decision to abandon medical school for genetics.
  • His father's disapproval stemmed from concerns about financial stability in academia.
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