Dr. Karl Herrup, a neurobiologist and author of 'How Not to Study a Disease: The Story of Alzheimer’s,' delves into the critical flaws of the amyloid cascade hypothesis in Alzheimer’s research. He argues that this longstanding theory may be hindering real progress toward a cure. Joined by Dr. Tommy Wood, they discuss the complexities of diagnosing Alzheimer’s, the roles of DNA damage, and the need for innovative approaches to treatment. Herrup emphasizes the importance of rethinking research methods to better understand this multifaceted disease.