The Peter Attia Drive

#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

127 snips
Jun 2, 2025
Paul Turek, a leading expert in male fertility and the founder of the Turek Clinic, dives into the intricate world of male reproductive health. He reveals the complex journey sperm undertake to fertilize an egg and discusses environmental factors like heat and toxins that can impair sperm quality. Turek also debunks myths surrounding testosterone replacement therapy and its effects on fertility, offering insights into preserving reproductive health. The conversation covers new advancements in reproductive medicine, including genetic testing and innovative treatments.
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INSIGHT

Sperm's Harsh Journey & Teamwork

  • Sperm face a highly hostile and complex journey to fertilize an egg, with only one making it out of millions.
  • Sperm coordinate in phalanxes to deactivate the female immune system and improve survival.
INSIGHT

Continuous Sperm Renewal & Meiosis

  • Sperm are produced continuously via meiosis creating genetic variation essential for evolution.
  • Unlike eggs, sperm renew constantly throughout a man's life, making ongoing environmental effects important.
INSIGHT

Sperm Maturation and Scenting

  • Sperm mature in the epididymis, developing motility and an olfactory sense to detect follicular fluid.
  • This chemical sensing enables sperm to navigate toward the egg with incredible sensitivity, akin to a shark sensing blood.
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