Real Health with Karl Henry

How to reverse weight gain in your 40s and 50s with Professor Donal O’Shea

Aug 14, 2025
Professor Donal O’Shea, HSE Lead for Obesity and an endocrinologist, dives into the pressing issue of obesity, particularly among Irish women aged 44 to 59. He discusses hormonal changes, the effectiveness of medications like Ozempic, and offers insights on how social media can combat diet myths. O’Shea highlights the complexities of weight management in midlife, including the impact of menopause and sleep quality. He also addresses societal pressures and the importance of medical oversight when using weight loss medications, wrapping up with optimistic trends in public health initiatives.
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ANECDOTE

Doctor Goes On Instagram To Counter Misinformation

  • Donal O'Shea started an Instagram project to share referenced, science-backed facts about nutrition and obesity.
  • His posts grew engagement and he plans to continue beyond the initial 12-week trial.
INSIGHT

Timing Matters For Weight Gain

  • The decade of greatest weight gain is 25–35, driven by life events like cars, kids and grief.
  • Obesity peaks at 40–55, especially in women, so prevention must target earlier decades.
INSIGHT

Ireland’s Obesity Rates Are Stabilising

  • Ireland's 2022 data shows obesity rates have leveled overall and childhood obesity did not spike during COVID.
  • This stability likely reflects sustained public health policies and visibility campaigns over the prior decade.
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