The Ty Beal Show

Nutritional Dark Matter and Regenerative Agriculture | Stephan van Vliet, PhD

Sep 23, 2025
Stephan van Vliet, PhD, a Professor of Nutrition at Utah State University, dives into the fascinating world of 'nutritional dark matter'—the hidden compounds in our food that impact our health. He discusses how regenerative agriculture enhances nutrient density, revealing the differences between pasture-raised and grain-fed beef. Stephan shares insights on the unique role of grazing animals in nutrient upcycling and offers practical tips for selecting nutrient-rich foods. His ongoing research promises exciting implications for sustainable food systems and human health.
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INSIGHT

Nutrition Facts Miss The Real Food

  • Nutrition facts panels show only a tiny fraction of food complexity and miss thousands of bioactive compounds.
  • These understudied compounds like anthocyanidins likely drive many health benefits of whole foods.
ANECDOTE

Egg Study Sparked Metabolomics Interest

  • Stephan van Vliet recounts a PhD study comparing whole eggs to egg whites where whole eggs boosted muscle anabolic response more.
  • He attributes the effect to yolk bioactives like carotenoids and peptides, not protein alone.
INSIGHT

Metabolomics Reveals Hidden Bioactives

  • Metabolomics profiles the small molecules in plants, soils, animals and foods to reveal bioactive metabolites.
  • These metabolites, often phytonutrients, can affect signaling pathways, insulin, and possibly cross the blood-brain barrier.
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