The Resetter Podcast with Dr. Mindy Understanding the Changes in Your Female Brain After 40 with Dr. Lisa Mosconi
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May 6, 2024 
Neuroscientist Dr. Lisa Mosconi and Dr. Mindy discuss menopausal brain transformations, hormonal shifts, brain function, grandmother hypothesis, hormone therapy impact, personalized toolkits, plant-forward diet benefits, estrogen's influence on brain health, and the importance of research on menopause's mental health implications.
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The Three Ps of Female Brain Development
- The female brain undergoes significant changes during puberty, pregnancy, and perimenopause, impacting brain development.
- These periods, known as the "three Ps," involve neuronal pruning and growth, unlike the linear brain aging observed in men.
Primal Reasons for Brain Changes
- Each of the "three Ps" (puberty, pregnancy, perimenopause) has a primal reason for brain restructuring.
- Puberty prepares for adulthood and social integration, pregnancy enhances maternal intuition, and perimenopause transitions to a new life phase.
Brain Changes in Puberty and Pregnancy
- Puberty involves significant neuronal pruning, eliminating unnecessary neurons to create a denser, more efficient brain, focusing on social cognition.
- Pregnancy further refines the brain, enhancing the theory of mind network for intuitive mothering, while also potentially causing temporary cognitive challenges.