The Resetter Podcast with Dr. Mindy Pelz cover image

The Resetter Podcast with Dr. Mindy Pelz

Understanding the Changes in Your Female Brain After 40 with Dr. Lisa Mosconi

May 6, 2024
Neuroscientist Dr. Lisa Mosconi and Dr. Mindy discuss menopausal brain transformations, hormonal shifts, brain function, grandmother hypothesis, hormone therapy impact, personalized toolkits, plant-forward diet benefits, estrogen's influence on brain health, and the importance of research on menopause's mental health implications.
01:26:57

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Quick takeaways

  • Menopause triggers brain changes for a new formation signaling growth and brain energy enhancement.
  • Chronic stress affects estrogen levels impacting menopausal symptoms and increasing risk of Alzheimer's.

Deep dives

Understanding the Brain Transition During Menopause

During menopause, a significant brain transition occurs as the brain undergoes pruning to eliminate what no longer serves it and make way for a new brain formation. This process, also seen during puberty and pregnancy, has a distinct purpose in each stage. Estradiol, a key hormone during this time, serves as a growth hormone that enhances neuron activity and energy production in the brain, influencing neurotransmitters like dopamine and serotonin, thereby affecting stress response.

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