The Dr. Hyman Show

Understanding the Impact of Chronic Stress on Your Brain | Dr. Robert Sapolsky

13 snips
Oct 16, 2024
Dr. Robert Sapolsky, a Stanford professor known for his stress research, joins to unveil the science behind chronic stress and its detrimental effects on the brain. He explains how long-term stress can damage the hippocampus, leading to cognitive decline. The conversation dives into the interplay between stress, genetics, and behavior, suggesting that free will may be an illusion. Sapolsky also shares useful strategies for managing stress, including mindfulness, exercise, and proper nutrition, highlighting their importance for overall health.
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INSIGHT

Chronic vs. Acute Stress

  • Chronic stress, unlike acute stress, is not what the stress response evolved for.
  • It's meant for short-term physical crises, not prolonged psychological distress.
INSIGHT

Stress and the Hippocampus

  • Chronic stress impacts the hippocampus, affecting learning, memory, and mood.
  • The hippocampus is highly sensitive to glucocorticoids like cortisol.
INSIGHT

Double-Edged Sword of Stress

  • Short-term stress enhances hippocampal function, improving memory and focus.
  • Chronic stress, however, depletes hippocampal neurons' energy, increasing vulnerability.
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